ea0073oc13.1 | Oral Communications 13: Pituitary and Neuroendocrinology | ECE2021
Perez-Rivas Luis Gustavo
, Simon Julia
, Albani Adriana
, Rotermund Roman
, Hermus Perez-Rivas
, Guillaume Assié
, Gadelha Monica
, Deutschbein Timo
, Flitsch Jörg
, Honegger Jürgen
, Rachinger Walter
, Stalla Günter
, Reincke Martin
, Theodoropoulou Marily
IntroductionTP53 mutations have been rarely reported in pituitary tumours. Recently two exploratory exome sequencing studies have identified somatic TP53 mutations in a small number of functional corticotroph tumours (6/18 and 4/10) with USP8 wild type (wt) status, suggesting that they may be more frequent than previously thought. Nevertheless, the clinical impact of those mutations is still unknown.AimTo det...